Research Fellow-Translational Neuroproteomics-Rossoll lab
Mayo Clinic
Jacksonville, FL 32224, USA
6/11/2026
Full time
Job Description
The Translational Neuroproteomics Laboratory (Rossoll Lab) is seeking a highly motivated Postdoctoral Research Fellow to join our Foundation-funded project to define the proteomic composition and molecular environment of pathological phospho-TDP-43 (pTDP-43) aggregates in human brain tissue and determine how these associated proteins contribute to neurodegeneration in sporadic frontotemporal lobar degeneration (FTLD-TDP).
The project integrates microscope-guided photolabeling/proximity proteomics in FFPE human brain tissue, affinity purification, data-independent acquisition LC-MS/MS, multiplexed spatial biology, proteomics data analysis, and functional validation in cellular and organotypic brain-slice culture models of TDP-43 proteinopathy.
The position offers an opportunity to work in a highly interactive neuroscience community at Mayo Clinic Florida, with access to world-class facilities, including the Multiomics Mass Spectrometry (MMS) core, and the Mayo Clinic brain bank.
Interested applicants should send a cover letter, CV, and contact information for three references to Dr. Wilfried Rossoll at rossoll.wilfried@mayo.edu.
Location: Jacksonville, Florida
Contact: Dr. Wilfried Rossoll - rossoll.wilfried@mayo.edu
More info: https://www.mayo.edu/research/labs/rossoll-lab
A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.
Qualifications
• Ph.D. (or equivalent) in Neuroscience, Cell or Molecular Biology, Biochemistry, or related field
• Strong background in molecular and cell biology techniques, biochemistry, and fluorescence microscopy
• Experience with tissue, cell culture, and proteomics is desirable
• Excellent organizational, communication, and teamwork skills
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
The Translational Neuroproteomics Laboratory (Rossoll Lab) is seeking a highly motivated Postdoctoral Research Fellow to join our Foundation-funded project to define the proteomic composition and molecular environment of pathological phospho-TDP-43 (pTDP-43) aggregates in human brain tissue and determine how these associated proteins contribute to neurodegeneration in sporadic frontotemporal lobar degeneration (FTLD-TDP).
The project integrates microscope-guided photolabeling/proximity proteomics in FFPE human brain tissue, affinity purification, data-independent acquisition LC-MS/MS, multiplexed spatial biology, proteomics data analysis, and functional validation in cellular and organotypic brain-slice culture models of TDP-43 proteinopathy.
The position offers an opportunity to work in a highly interactive neuroscience community at Mayo Clinic Florida, with access to world-class facilities, including the Multiomics Mass Spectrometry (MMS) core, and the Mayo Clinic brain bank.
Interested applicants should send a cover letter, CV, and contact information for three references to Dr. Wilfried Rossoll at rossoll.wilfried@mayo.edu.
Location: Jacksonville, Florida
Contact: Dr. Wilfried Rossoll - rossoll.wilfried@mayo.edu
More info: https://www.mayo.edu/research/labs/rossoll-lab
A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.
Qualifications
• Ph.D. (or equivalent) in Neuroscience, Cell or Molecular Biology, Biochemistry, or related field
• Strong background in molecular and cell biology techniques, biochemistry, and fluorescence microscopy
• Experience with tissue, cell culture, and proteomics is desirable
• Excellent organizational, communication, and teamwork skills
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.